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Suboxone Detoxification

  • Significant withdrawal symptoms are unusual during gradual Suboxone or Subutex dose taper.
  • The rate of dose reduction should be determined in collaboration with the patient.
  • Patient may have possible feelings of less energy, lower appetite, irritability, difficulty in sleeping, etc. However, these effects are transitory and should only last a few days.
  • Realistic goals for reduction should be established.
  • Generally, the more gradual the reduction, the better the outcome.
  • Patients should expect to experience some withdrawal discomfort once they reach low doses or stop taking Suboxone or Subutex completely.
  • Slow down or stop the dose reductions if:
    • The patient starts to reuse opioid
    • The patient's physical, psychological, or social well-being begins to deteriorate
  • Examples of dose reduction rates and schedules are shown on the following chart.

Dose Reduction Schedule
Days Dose Schedule
1 - 4 days 8 mg buprenorphine
5 - 8 days 4 mg buprenorphine
9 - 12 days 2 mg buprenorphine
13 - 16 days 1 mg buprenorphine
17 - 30 days Non-narcotic medication
~ 23 - 30 days Start Naltrexone
 
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